Suicidally dosed Ecstasy consumption
by
Hinkelbein J, Gabel A, Volz M, Ellinger K.
Institut fur Anasthesiologie und Operative Intensivmedizin,
Universitatsklinikum Mannheim.
Anaesthesist 2003 Jan;52(1):51-4
ABSTRACTThe case of a 16-year-old female patient is reported, who has taken in 30 tablets of Ecstasy in a suicide attempt. Initially were seen a tachycardia, hyperdynamic circulation, dehydration, leg-myocloni in the awake excited female patient. For prophylaxis of aspiration general anaesthesia and intubation with following gastric lavage were performed. During the intensive care treatment the high blood pressure persisted, although general anaesthesia and anti-hypertensive therapy was continued. After extubation the neurologic status of the patient was normal. Emergency physicians see more and more often Ecstasy-intoxications. Signs of an acute intoxication with Ecstasy are a sympathomimetic reaction with tachycardia, hypertonic blood pressure and cardiac arrhythmia as well as fever, respiratory and renal insufficiancy, rhabdomyolysis, cerebral edema and convulsion. A specific antidote does not exist; the symptomatic therapy consists of airway management, hemodynamic stabilisation, primary drug-elimination and, in case of need, application of betablockers and relaxants.Oxidative stress
Locomotor effects
MDMA v fenfluramine
Baboons like Ecstasy
Cocaine sensitisation
Anti-Parkinsonian effect
Cutaneous vasoconstriction
MDMA and the mitochondria
Ecstasy/MDMA and cannabis
Arginine-vasopressin release
Phosphatidylinositol turnover
MDMA, loud noise and the heart
MDMA, antihistamines and serotonin
MDMA, HIV and antiretroviral agents
Serotonin, noradrenline and dopamine
MDMA/polydrug users in the UK and Italy
and further reading
Refs
HOME
HedWeb
Nootropics
cocaine.wiki
Future Opioids
BLTC Research
MDMA/Ecstasy
Superhapiness?
Utopian Surgery?
The Abolitionist Project
The Hedonistic Imperative
The Reproductive Revolution
Critique of Huxley's Brave New World
The Good Drug Guide
The Responsible Parent's Guide
To Healthy Mood Boosters For All The Family